Search on: CELL PROLIFERATION FACTOR HCF 
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Descriptor English:   Host Cell Factor C1 
Descriptor Spanish:   Factor C1 de la Célula Huésped 
Descriptor Portuguese:   Fator C1 de Célula Hospedeira 
Synonyms English:   C1 Host Cell Factor
Cell Proliferation Factor HCF
HCFC1 Protein  
Tree Number:   D12.776.660.478
D12.776.930.325
Definition English:   A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION. 
History Note English:   2006(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51188 
Unique Identifier:   D051863 

Occurrence in VHL:
 

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